TMEM192

Across TCGA patient cohorts, TMEM192 protein abundance is significantly associated with the RNA expression of many other genes, with 13,411 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM192-associated genes across cancer lineages are ZWINT, TOPBP1, and PTTG1. Each is linked with TMEM192 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM192-to-partner and partner-to-TMEM192 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM192 versus ZWINT in HNSC, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM192→partner) and Y-score (partner→TMEM192) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZWINT →	-1.273	-0.316	<.001	.001	3	5
LSCC	TOPBP1 →	-0.722	-0.282	<.001	<.001	3	5
UCEC	PTTG1 →	-0.999	-0.495	<.001	.001	3	5
UCEC	ALYREF →	-1.269	-0.544	.003	.001	3	5
OV	TRAPPC11 →	+0.516	+0.381	.001	<.001	3	5
OV	GATB →	+0.699	+0.480	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,411 associations by consensus.

TMEM192 vs ZWINT — HNSC

Explore this scatter interactively →