TLCD4-RWDD3

Across TCGA patient cohorts, TLCD4-RWDD3 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TLCD4-RWDD3-associated genes across cancer lineages are C5orf64, LILRP1, and MIR147A. Each is linked with TLCD4-RWDD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TLCD4-RWDD3-to-partner and partner-to-TLCD4-RWDD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C5orf64 grouped by TLCD4-RWDD3-low versus TLCD4-RWDD3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD4-RWDD3→partner) and Y-score (partner→TLCD4-RWDD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C5orf64 →	+0.106	+3.697	<.001	.007	3	1
UCEC	LILRP1 →	+0.146	+3.422	.002	.009	3	1
UCEC	MIR147A →	+0.339	+4.260	<.001	.007	3	1
UCEC	IGHD1-26 →	+1.170	+4.069	<.001	.002	3	1
UCEC	IGHD3-9 →	+1.795	+4.120	.005	.001	3	1
UCEC	HMGB1P17 →	+0.241	+3.200	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

C5orf64 by TLCD4-RWDD3 expression — UCEC

Explore this box plot interactively →