TLCD4-RWDD3

Across TCGA pan-cancer cohorts, TLCD4-RWDD3 RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated TLCD4-RWDD3 data layer compared with 1 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher TLCD4-RWDD3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TLCD4-RWDD3 expression acts as an unfavorable survival marker, although some lineages such as READ and HNSC show a favorable association.

MESO, LGG, and READ are the cancer types where TLCD4-RWDD3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	All	0.234	0.485	<.001	87	view →
LGG	DFS	Median	All	0.658	0.814	<.001	47	view →
READ	OS	Median	II,III,IV	0.882	0.318	<.001	40	view →
HNSC	OS	Median	All	0.818	0.717	.004	36	view →
UCS	DFS	Tertile	IV	0.978	0.403	.024	26	view →
KIRP	DFS	Median	IV	0.038	0.527	.010	24	view →
KICH	DFS	Median	III,IV	0.374	0.901	.009	20	view →
ESCA	OS	Median	IV	0.222	0.698	.006	18	view →
LUSC	DFS	Quartile	II,III,IV	0.203	0.460	.004	17	view →
UVM	DFS	Median	III,IV	0.220	0.664	.020	16	view →
CHOL	OS	Median	III,IV	0.286	1.000	.008	15	view →
CESC	DFS	Tertile	All	0.779	0.883	.006	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

TLCD4-RWDD3–MESO (DFS)

Open the MESO breakdown →