Q-omics provides the consensus-scored TEN1-CDK3 profile across patient tissues and cancer cell-line models. TEN1-CDK3 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, TEN1-CDK3 is differentially expressed in 11, with the highest sampling consensus in KIRC. Additionally, TEN1-CDK3 RNA expression shows 19,337 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight HNSC, KIRC, and THYM as cancer lineages where TEN1-CDK3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TEN1-CDK3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TEN1-CDK3 survival associations across molecular data types. TEN1-CDK3 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TEN1-CDK3 RNA expression–survival associations across cancer types. High TEN1-CDK3 expression shows unfavorable associations in ACC, KIRC and COAD, but favorable associations in HNSC, PAAD and BLCA. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for TEN1-CDK3 RNA expression.
This table summarizes TEN1-CDK3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for TEN1-CDK3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TEN1-CDK3 shows lower tumor expression in KICH and BRCA and higher tumor expression in KIRC, BLCA, COAD and CHOL. The KIRC box plot shows higher TEN1-CDK3 RNA expression in tumor versus normal tissue (log2 FC = +0.295, t-test p < 0.001).
This table shows molecular features associated with TEN1-CDK3 in patient tissues and cancer cell lines. In patient samples, TEN1-CDK3 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
