TEN1-CDK3

Across TCGA pan-cancer cohorts, TEN1-CDK3 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TEN1-CDK3’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TEN1-CDK3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TEN1-CDK3 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KIRC, BLCA, and KICH are the cancer types where TEN1-CDK3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TEN1-CDK3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.295	<.001	11	view →
BLCA	All	III,IV	+0.520	.001	7	view →
KICH	Female	All	−0.309	<.001	6	view →
COAD	All	II,III,IV	+0.278	.002	5	view →
BRCA	All	All	−0.198	<.001	4	view →
CHOL	All	All	+0.735	<.001	3	view →
LUSC	Male	All	+0.340	.008	3	view →
LIHC	All	All	+0.246	.001	3	view →
READ	Female	All	+0.740	.016	2	view →
PRAD	All	All	+0.231	.003	2	view →
STAD	All	II,III,IV	+0.215	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TEN1-CDK3–KIRC

Open the KIRC breakdown →