TBC1D3P1-DHX40P1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TBC1D3P1-DHX40P1 mutation is significantly associated with the RNA expression of many other genes, with 78 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D3P1-DHX40P1-associated genes across cancer lineages are RNA5SP420, FTMT, and PSG9. Each is linked with TBC1D3P1-DHX40P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D3P1-DHX40P1-to-partner and partner-to-TBC1D3P1-DHX40P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP420 grouped by TBC1D3P1-DHX40P1-low versus TBC1D3P1-DHX40P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D3P1-DHX40P1→partner) and Y-score (partner→TBC1D3P1-DHX40P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP420 →+1.114+3.289<.001.00132
UCECFTMT →+0.205+2.756.002.00631
UCECPSG9 →+0.163+3.286<.001.00131
UCECRNA5SP124 →+0.540+2.903<.001.00431
UCECRNU6-391P →+0.350+4.027<.001.00131
UCECSNORD82 →+0.831+3.454<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 78 associations by consensus.

RNA5SP420 by TBC1D3P1-DHX40P1 expression — UCEC

Box plot of RNA5SP420 in TBC1D3P1-DHX40P1-low vs TBC1D3P1-DHX40P1-high samples in UCEC.

Explore this box plot interactively →

Exploration