TBC1D3P1-DHX40P1

Across TCGA pan-cancer cohorts, TBC1D3P1-DHX40P1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated TBC1D3P1-DHX40P1 data layer compared with 3 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher TBC1D3P1-DHX40P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TBC1D3P1-DHX40P1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCS show a favorable association.

KIRP, READ, and THYM are the cancer types where TBC1D3P1-DHX40P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.398	0.862	<.001	90	view →
READ	DFS	Tertile	All	0.343	0.828	<.001	81	view →
THYM	OS	Tertile	All	0.830	0.980	<.001	75	view →
LUAD	DFS	Tertile	II,III,IV	0.792	0.576	.005	60	view →
ACC	OS	Tertile	III,IV	0.145	0.766	<.001	45	view →
SKCM	OS	Tertile	III,IV	0.413	0.712	.032	27	view →
PCPG	OS	Tertile	All	0.009	0.946	<.001	27	view →
UCS	DFS	Tertile	III,IV	0.770	0.203	.036	18	view →
OV	DFS	Tertile	IV	0.207	0.472	.030	18	view →
PRAD	DFS	Tertile	All	0.814	0.939	.004	18	view →
KIRC	DFS	Tertile	All	0.220	0.630	.020	12	view →
STAD	OS	Tertile	All	0.228	0.438	.039	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

TBC1D3P1-DHX40P1–KIRP (DFS)

Open the KIRP breakdown →