TAS2R30

Across TCGA patient cohorts, TAS2R30 mutation is significantly associated with the RNA expression of many other genes, with 61 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAS2R30-associated genes across cancer lineages are GPR32, GPR148, and RNU6-263P. Each is linked with TAS2R30 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAS2R30-to-partner and partner-to-TAS2R30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR32 grouped by TAS2R30-low versus TAS2R30-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R30→partner) and Y-score (partner→TAS2R30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GPR32 →	+0.064	+5.145	.001	.007	3	1
BLCA	GPR148 →	+0.049	+5.106	<.001	.008	3	1
BLCA	RNU6-263P →	+0.650	+6.289	<.001	.001	3	1
COAD	RNA5SP90 →	+0.794	+5.017	<.001	.009	3	1
COAD	ATP5PBP2 →	+0.293	+5.017	<.001	.009	3	1
COAD	RPL32P19 →	+0.183	+5.017	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

GPR32 by TAS2R30 expression — COAD

Explore this box plot interactively →