TALDO1

Across TCGA patient cohorts, TALDO1 mutation is significantly associated with the RNA expression of many other genes, with 427 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TALDO1-associated genes across cancer lineages are HARS2, MTCO2P9, and RNU6-42P. Each is linked with TALDO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TALDO1-to-partner and partner-to-TALDO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HARS2 grouped by TALDO1-low versus TALDO1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TALDO1→partner) and Y-score (partner→TALDO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HARS2 →	+0.403	+2.394	.002	.002	3	2
BLCA	MTCO2P9 →	+0.030	+4.500	<.001	.004	3	2
UCEC	RNU6-42P →	+0.649	+2.294	<.001	.001	3	2
BLCA	LY6L →	+0.325	+2.639	.009	.008	3	1
BLCA	MIR4433B →	+0.163	+4.233	<.001	.006	3	1
BLCA	LINC01901 →	+0.708	+3.555	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 427 associations by consensus.

HARS2 by TALDO1 expression — UCEC

Explore this box plot interactively →