TALDO1

Across TCGA pan-cancer cohorts, TALDO1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TALDO1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TALDO1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TALDO1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

COAD, LIHC, and KIRP are the cancer types where TALDO1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TALDO1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	III,IV	+0.982	<.001	11	view →
LIHC	Male	II,III,IV	+1.589	<.001	9	view →
KIRP	All	II,III,IV	+1.384	<.001	9	view →
KICH	Female	II,III,IV	−1.054	<.001	8	view →
LUSC	Male	All	+0.814	<.001	7	view →
UCEC	All	All	+0.883	<.001	6	view →
LUAD	All	All	+0.482	<.001	6	view →
BRCA	Female	All	+0.240	.001	6	view →
STAD	All	All	+0.499	.003	5	view →
CHOL	All	All	+1.331	.002	3	view →
PRAD	All	All	+0.236	.043	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TALDO1–COAD

Open the COAD breakdown →