Q-omics provides the consensus-scored MIR4433B profile across patient tissues and cancer cell-line models. MIR4433B expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, MIR4433B is differentially expressed in 1, with the highest sampling consensus in LUSC. Additionally, MIR4433B RNA expression shows 8,525 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight COAD, LUSC, and TGCT as cancer lineages where MIR4433B shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4433B — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4433B survival associations across molecular data types. MIR4433B RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4433B RNA expression–survival associations across cancer types. High MIR4433B expression shows unfavorable associations in COAD, KIRC, STAD, PCPG, SARC and BLCA. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify COAD as the clearest survival context for MIR4433B RNA expression.
This table summarizes MIR4433B tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4433B. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4433B shows higher tumor expression in LUSC. The LUSC box plot shows higher MIR4433B RNA expression in tumor versus normal tissue (log2 FC = +0.051, t-test p = .045).
This table shows molecular features associated with MIR4433B in patient tissues and cancer cell lines. In patient samples, MIR4433B shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
