TAAR5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TAAR5 mutation is significantly associated with the RNA expression of many other genes, with 1,869 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAAR5-associated genes across cancer lineages are RNY4P14, RNA5SP143, and CCT8. Each is linked with TAAR5 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAAR5-to-partner and partner-to-TAAR5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNY4P14 grouped by TAAR5-low versus TAAR5-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAAR5→partner) and Y-score (partner→TAAR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNY4P14 →+0.317+5.147<.001.00333
COADRNA5SP143 →+0.551+3.893<.001<.00133
UCECCCT8 →+0.496+2.815.001.00132
UCECMED19 →+0.364+2.609.005.00632
UCECH2AZ1 →+0.695+2.447<.001.00132
UCECCEP57 →+0.481+3.732.004<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,869 associations by consensus.

RNY4P14 by TAAR5 expression — BLCA

Box plot of RNY4P14 in TAAR5-low vs TAAR5-high samples in BLCA.

Explore this box plot interactively →

Exploration