SYT13

Across TCGA patient cohorts, SYT13 mutation is significantly associated with the RNA expression of many other genes, with 1,159 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYT13-associated genes across cancer lineages are DPH3, LINC00588, and RNA5SP198. Each is linked with SYT13 in more than 2 cancer types. Because this analysis shows association rather than direction, both SYT13-to-partner and partner-to-SYT13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DPH3 grouped by SYT13-low versus SYT13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT13→partner) and Y-score (partner→SYT13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DPH3 →	+0.522	+2.625	.001	.005	3	3
CESC	LINC00588 →	+0.060	+5.418	<.001	.005	3	2
CESC	RNA5SP198 →	+0.411	+6.144	<.001	.001	3	2
CESC	NF1P6 →	+0.331	+6.342	<.001	.001	3	2
CESC	RN7SL447P →	+0.230	+5.201	<.001	.007	3	2
CESC	RN7SL66P →	+0.158	+5.010	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,159 associations by consensus.

DPH3 by SYT13 expression — UCEC

Explore this box plot interactively →