Q-omics provides the consensus-scored LINC00588 profile across patient tissues and cancer cell-line models. LINC00588 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, LINC00588 is differentially expressed in 5, with the highest sampling consensus in KICH. Additionally, LINC00588 RNA expression shows 9,411 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight UVM, and KICH as cancer lineages where LINC00588 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00588 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00588 survival associations across molecular data types. LINC00588 RNA expression shows survival associations in the most cancer types (16), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00588 RNA expression–survival associations across cancer types. High LINC00588 expression shows unfavorable associations in UVM, KIRP, ACC, BLCA, ESCA and THYM. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for LINC00588 RNA expression.
This table summarizes LINC00588 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00588. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00588 shows lower tumor expression in KIRP, KIRC, LUAD and LUSC and higher tumor expression in KICH. The KICH box plot shows higher LINC00588 RNA expression in tumor versus normal tissue (log2 FC = +2.519, t-test p < 0.001).
This table shows molecular features associated with LINC00588 in patient tissues and cancer cell lines. In patient samples, LINC00588 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, LINC00588 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in NCI60_ALL.
