SUV39H2

Across TCGA patient cohorts, SUV39H2 mutation is significantly associated with the RNA expression of many other genes, with 240 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUV39H2-associated genes across cancer lineages are RNU6-1228P, FTLP18, and SLC29A4P2. Each is linked with SUV39H2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUV39H2-to-partner and partner-to-SUV39H2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1228P grouped by SUV39H2-low versus SUV39H2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUV39H2→partner) and Y-score (partner→SUV39H2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1228P →	+0.175	+4.049	.001	<.001	3	2
BLCA	FTLP18 →	+0.059	+7.640	<.001	.009	3	2
SKCM	SLC29A4P2 →	+0.032	+4.867	<.001	.005	3	2
COAD	SIX6 →	+0.207	+5.542	<.001	<.001	3	1
COAD	TMEM167AP1 →	+0.368	+4.790	<.001	.006	3	1
COAD	LINC01029 →	+0.276	+4.543	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 240 associations by consensus.

RNU6-1228P by SUV39H2 expression — UCEC

Explore this box plot interactively →