STRA8

Across TCGA patient cohorts, STRA8 protein abundance is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible STRA8-associated genes across cancer lineages are PLXDC1, ILRUN, and SNORD114-2. Each is linked with STRA8 in more than 1 cancer types. Because this analysis shows association rather than direction, both STRA8-to-partner and partner-to-STRA8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STRA8 versus PLXDC1 in LUAD, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STRA8→partner) and Y-score (partner→STRA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PLXDC1 →	-1.887	-1.647	<.001	.007	3	1
LUAD	ILRUN →	-0.714	-1.587	.002	.009	3	1
LUAD	SNORD114-2 →	+2.444	+1.870	.004	.002	3	1
LUAD	MIR187 →	+1.931	+1.666	.001	<.001	3	1
LUAD	HMGB3P18 →	+0.155	+2.214	.003	.006	3	1
LUAD	MIR1197 →	+1.271	+2.200	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

STRA8 vs PLXDC1 — LUAD

Explore this scatter interactively →