STON1-GTF2A1L

Across TCGA patient cohorts, STON1-GTF2A1L mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STON1-GTF2A1L-associated genes across cancer lineages are CDK1, INPP4B, and VHL. Each is linked with STON1-GTF2A1L in more than 2 cancer types. Because this analysis shows association rather than direction, both STON1-GTF2A1L-to-partner and partner-to-STON1-GTF2A1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDK1 grouped by STON1-GTF2A1L-low versus STON1-GTF2A1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STON1-GTF2A1L→partner) and Y-score (partner→STON1-GTF2A1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDK1 →	+0.128	+1.807	.016	.025	3	3
UCEC	INPP4B →	-0.264	-1.807	.021	.024	3	2
UCEC	VHL →	-1.320	-2.392	<.001	<.001	3	2
UCEC	STAT3_pY705 →	-0.474	-2.392	<.001	<.001	3	2
UCEC	BRCA2 →	-0.104	-2.211	.023	.010	3	2
UCEC	53BP1 →	+0.274	+2.459	.023	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

CDK1 by STON1-GTF2A1L expression — UCEC

Explore this box plot interactively →