STON1-GTF2A1L

Across TCGA pan-cancer cohorts, STON1-GTF2A1L RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of STON1-GTF2A1L’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where STON1-GTF2A1L RNA is repressed in tumor relative to normal tissue. In most cancer types STON1-GTF2A1L is over-expressed in tumor, although a few such as KICH and BLCA show the opposite, repressed pattern.

KICH, BLCA, and THCA are the cancer types where STON1-GTF2A1L tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STON1-GTF2A1L RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−0.219	<.001	10	view →
BLCA	All	III,IV	−0.722	.001	8	view →
THCA	Female	All	−0.236	<.001	8	view →
UCEC	All	All	−0.354	.001	6	view →
STAD	All	All	−0.281	.002	6	view →
BRCA	All	All	−0.188	<.001	6	view →
HNSC	Female	All	+0.053	.003	6	view →
LUSC	All	All	−0.154	<.001	5	view →
LUAD	Female	All	−0.120	<.001	4	view →
KIRP	Male	All	−0.074	.021	4	view →
COAD	Female	II,III,IV	−0.054	.013	3	view →
READ	All	All	−0.410	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

STON1-GTF2A1L–KICH

Open the KICH breakdown →