STIMATE-MUSTN1

Across TCGA patient cohorts, STIMATE-MUSTN1 mutation is significantly associated with the RNA expression of many other genes, with 100 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STIMATE-MUSTN1-associated genes across cancer lineages are SUGT1P4, SNORD114-4, and RNU1-43P. Each is linked with STIMATE-MUSTN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STIMATE-MUSTN1-to-partner and partner-to-STIMATE-MUSTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SUGT1P4 grouped by STIMATE-MUSTN1-low versus STIMATE-MUSTN1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STIMATE-MUSTN1→partner) and Y-score (partner→STIMATE-MUSTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SUGT1P4 →	+0.208	+7.954	<.001	.008	3	2
UCEC	SNORD114-4 →	+0.405	+4.555	.001	.005	3	2
UCEC	RNU1-43P →	+0.438	+4.400	<.001	.006	3	2
UCEC	MIR920 →	+0.957	+3.549	<.001	.002	3	2
UCEC	ZNF25-DT →	+0.269	+3.179	<.001	.006	3	2
HNSC	VN1R36P →	+0.104	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 100 associations by consensus.

SUGT1P4 by STIMATE-MUSTN1 expression — HNSC

Explore this box plot interactively →