STIMATE-MUSTN1

Across TCGA pan-cancer cohorts, STIMATE-MUSTN1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated STIMATE-MUSTN1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher STIMATE-MUSTN1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated STIMATE-MUSTN1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

KIRC, ACC, and HNSC are the cancer types where STIMATE-MUSTN1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.528	0.696	<.001	135	view →
ACC	OS	Median	All	0.408	0.832	<.001	127	view →
HNSC	OS	Quartile	II,III,IV	0.566	0.301	.002	86	view →
BLCA	DFS	Quartile	II,III,IV	0.421	0.261	.005	57	view →
LGG	DFS	Median	All	0.243	0.472	<.001	54	view →
OV	OS	Quartile	III,IV	0.812	0.894	.005	44	view →
UCS	DFS	Tertile	IV	0.857	0.237	.024	34	view →
SCLC	DFS	Median	III,IV	0.701	0.309	.002	31	view →
CESC	DFS	Quartile	III,IV	0.153	0.714	.001	26	view →
PRAD	DFS	Tertile	All	0.829	0.945	<.001	22	view →
UVM	OS	Quartile	All	1.000	0.662	.017	19	view →
SKCM	OS	Tertile	IV	1.000	0.213	.008	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

STIMATE-MUSTN1–KIRC (DFS)

Open the KIRC breakdown →