Across TCGA pan-cancer cohorts, STIMATE-MUSTN1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of STIMATE-MUSTN1’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where STIMATE-MUSTN1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types STIMATE-MUSTN1 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.
LIHC, LUSC, and LUAD are the cancer types where STIMATE-MUSTN1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STIMATE-MUSTN1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.