Q-omics provides the consensus-scored ZNF25-DT profile across patient tissues and cancer cell-line models. ZNF25-DT expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in SKCM. Additionally, ZNF25-DT RNA expression shows 6,412 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight SKCM, and STAD as cancer lineages where ZNF25-DT shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes ZNF25-DT survival associations across molecular data types. ZNF25-DT RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

ZNF25-DT data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	SKCM (63)	view →

This table ranks reproducible ZNF25-DT RNA expression–survival associations across cancer types. High ZNF25-DT expression shows unfavorable associations in SKCM, UCS, LUSC, KICH, SARC and STAD. The SKCM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for ZNF25-DT RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	IV	0.179	0.727	<.001	63	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
LUSC	DFS	Tertile	II,III,IV	0.079	0.750	<.001	36	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	36	view →
SARC	OS	Tertile	All	0.288	0.535	.011	12	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →

Pink = unfavorable, green = favorable. all 9 lineages →

ZNF25-DT-SKCM (OS)

Kaplan–Meier survival curve for ZNF25-DT RNA expression in SKCM: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with ZNF25-DT in patient tissues and cancer cell lines. In patient samples, ZNF25-DT shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	6,412	STAD (5961)	view →
RNA	4,004	HNSC (686)	view →