Across TCGA patient cohorts, ZNF25-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,412 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ZNF25-DT-associated GO terms across cancer lineages are Ribose phosphate biosynthetic process, Regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, and Vesicle localization. Each is linked with ZNF25-DT in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF25-DT-to-partner and partner-to-ZNF25-DT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF25-DT→partner) and Y-score (partner→ZNF25-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Ribose phosphate biosynthetic process →	+0.093	+0.174	<.001	<.001	3	11
ESCA	Regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.110	+0.170	<.001	.003	3	9
STAD	Vesicle localization →	+0.083	+0.188	<.001	<.001	3	9
STAD	Establishment of protein localization to membrane →	+0.092	+0.183	<.001	<.001	3	8
STAD	Autophagosome maturation →	+0.091	+0.161	<.001	<.001	3	8
STAD	Mitochondrial electron transport, ubiquinol to cytochrome c →	+0.084	+0.147	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,412 associations by consensus.

Exploration

ZNF25-DT survival (RNA) · tumor vs normal (RNA) · all ZNF25-DT data types