STAB1

Across TCGA cell cohorts, STAB1 mutation is significantly associated with the RNA expression of many other genes, with 2,157 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STAB1-associated genes across cancer lineages are FAM98C, POMGNT2, and CNNM2. Each is linked with STAB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both STAB1-to-partner and partner-to-STAB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM98C grouped by STAB1-low versus STAB1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAB1→partner) and Y-score (partner→STAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FAM98C →	+0.829	+3.366	<.001	.002	3	3
LARGE_INTESTINE	POMGNT2 →	+0.588	+1.584	.003	.005	3	3
LARGE_INTESTINE	CNNM2 →	+0.592	+1.889	<.001	<.001	3	3
LARGE_INTESTINE	MFSD4B →	+0.319	+1.610	.003	.006	3	3
SOFT_TISSUE	KRTAP5-6 →	+0.112	+4.186	.003	.001	3	3
BLOOD_Leukemia	BMPR1A →	+1.087	+2.674	.004	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,157 associations by consensus.

FAM98C by STAB1 expression — BLOOD_Leukemia

Explore this box plot interactively →