ST8SIA3

Across TCGA cell cohorts, ST8SIA3 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ST8SIA3-associated genes across cancer lineages are CCL18, SCN10A, and STATH. Each is linked with ST8SIA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST8SIA3-to-partner and partner-to-ST8SIA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL18 grouped by ST8SIA3-low versus ST8SIA3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA3→partner) and Y-score (partner→ST8SIA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CCL18 →	+0.029	+4.212	.002	.007	3	2
LUNG_NSCLC_LUAD	SCN10A →	+0.004	+4.662	<.001	.005	3	1
BLOOD_Leukemia	STATH →	+0.413	+4.133	<.001	.003	3	1
BLOOD_Leukemia	OR11H1 →	+0.063	+4.786	<.001	<.001	3	1
BLOOD_Leukemia	SLCO1C1 →	+0.078	+5.121	<.001	<.001	3	1
BLOOD_Leukemia	ARHGAP36 →	+0.018	+3.944	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

CCL18 by ST8SIA3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →