ST8SIA2

Across TCGA patient cohorts, ST8SIA2 mutation is significantly associated with the RNA expression of many other genes, with 2,629 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ST8SIA2-associated genes across cancer lineages are RN7SL66P, MSANTD3, and HOXC-AS3. Each is linked with ST8SIA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ST8SIA2-to-partner and partner-to-ST8SIA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL66P grouped by ST8SIA2-low versus ST8SIA2-high in KIRP.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA2→partner) and Y-score (partner→ST8SIA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	RN7SL66P →	+0.224	+3.830	<.001	.006	3	3
SKCM	MSANTD3 →	+0.488	+2.398	.003	<.001	3	3
UCEC	HOXC-AS3 →	+0.659	+1.963	<.001	<.001	3	3
UCEC	NUDT22 →	+0.312	+2.828	.005	.001	3	2
UCEC	ALDOA →	+0.400	+2.169	.003	<.001	3	2
UCEC	HIRIP3 →	+0.420	+2.496	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,629 associations by consensus.

RN7SL66P by ST8SIA2 expression — KIRP

Explore this box plot interactively →