ST6GALNAC6

Across TCGA patient cohorts, ST6GALNAC6 protein abundance is significantly associated with the RNA expression of many other genes, with 67 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ST6GALNAC6-associated genes across cancer lineages are VSIG1, SCNN1B, and ZNF24. Each is linked with ST6GALNAC6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC6-to-partner and partner-to-ST6GALNAC6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST6GALNAC6 versus VSIG1 in LSCC, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC6→partner) and Y-score (partner→ST6GALNAC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VSIG1 →	+0.885	+3.219	.002	.006	3	1
LSCC	SCNN1B →	+3.324	+3.219	.009	.006	3	1
LSCC	ZNF24 →	+0.509	+3.520	.002	.005	3	1
LSCC	FSCB →	+0.740	+3.219	.003	.006	3	1
LSCC	CXCL17 →	+2.764	+3.219	.007	.006	3	1
LSCC	PLCE1-AS2 →	+1.550	+3.520	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

ST6GALNAC6 vs VSIG1 — LSCC

Explore this scatter interactively →