ST18

Across TCGA patient cohorts, ST18 protein abundance is significantly associated with the RNA expression of many other genes, with 3,108 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ST18-associated genes across cancer lineages are MRPS14, SLX4IP, and TMEM184C. Each is linked with ST18 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST18-to-partner and partner-to-ST18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST18 versus MRPS14 in LSCC, with a Pearson correlation of -0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST18→partner) and Y-score (partner→ST18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MRPS14 →	-0.609	-1.382	<.001	<.001	3	2
LSCC	SLX4IP →	-0.633	-1.093	.002	.003	3	2
GBM	TMEM184C →	-0.422	-1.431	.001	.003	3	2
LSCC	SYCP2 →	-1.071	-0.940	.001	.003	3	2
LSCC	MIR181B2 →	-0.838	-1.387	.004	.002	3	2
GBM	STX17-AS1 →	-0.465	-1.174	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,108 associations by consensus.

ST18 vs MRPS14 — LSCC

Explore this scatter interactively →