SRRD

Across TCGA patient cohorts, SRRD protein abundance is significantly associated with the RNA expression of many other genes, with 1,227 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SRRD-associated genes across cancer lineages are ZNF583, SCUBE1-AS1, and USP32P2. Each is linked with SRRD in more than 1 cancer types. Because this analysis shows association rather than direction, both SRRD-to-partner and partner-to-SRRD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRRD versus ZNF583 in HNSC, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRRD→partner) and Y-score (partner→SRRD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZNF583 →	+0.700	+1.333	.007	.005	3	1
HNSC	SCUBE1-AS1 →	+0.099	+0.416	.005	.004	3	1
HNSC	USP32P2 →	+0.243	+0.416	.002	.004	3	1
HNSC	KRT18P45 →	+0.120	+1.003	.002	.005	3	1
HNSC	IGHV3-65 →	+0.616	+0.944	.001	.002	3	1
GBM	DICER1 →	+0.319	+0.402	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,227 associations by consensus.

SRRD vs ZNF583 — HNSC

Explore this scatter interactively →