SRPX

Across TCGA patient cohorts, SRPX RNA expression is significantly associated with the protein abundance of many other proteins, with 22,868 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SRPX-associated proteins across cancer lineages are RSU1, SORBS3, and PARVA. Each is linked with SRPX in more than 9 cancer types. Because this analysis shows association rather than direction, both SRPX-to-partner and partner-to-SRPX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRPX versus RSU1 in UCEC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SRPX→partner) and Y-score (partner→SRPX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RSU1 →	+0.530	+1.220	<.001	<.001	3	10
UCEC	SORBS3 →	+0.646	+1.043	<.001	<.001	3	10
UCEC	PARVA →	+0.678	+1.269	<.001	<.001	3	10
UCEC	ILK →	+0.590	+1.120	<.001	<.001	3	10
UCEC	KANK2 →	+0.769	+1.192	<.001	<.001	3	10
BRCA	LRP1 →	+0.657	+1.497	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,868 associations by consensus.

SRPX vs RSU1 — UCEC

Explore this scatter interactively →