SPCS3-AS1

Across TCGA patient cohorts, SPCS3-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,281 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPCS3-AS1-associated GO terms across cancer lineages are Regulation of RNA splicing, Vacuole organization, and Negative regulation of mRNA metabolic process. Each is linked with SPCS3-AS1 in more than 19 cancer types. Because this analysis shows association rather than direction, both SPCS3-AS1-to-partner and partner-to-SPCS3-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by SPCS3-AS1-low versus SPCS3-AS1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPCS3-AS1→partner) and Y-score (partner→SPCS3-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of RNA splicing →	+0.072	+0.055	<.001	<.001	3	20
STAD	Vacuole organization →	+0.062	+0.054	<.001	<.001	3	19
STAD	Negative regulation of mRNA metabolic process →	+0.063	+0.053	<.001	<.001	3	18
ESCA	Nucleotide-excision repair →	+0.056	+0.044	<.001	.001	3	18
STAD	TORC1 signaling →	+0.065	+0.052	<.001	<.001	3	18
ESCA	Autophagy of mitochondrion →	+0.063	+0.077	<.001	.003	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,281 associations by consensus.

Regulation of RNA splicing by SPCS3-AS1 expression — STAD

Explore this box plot interactively →