SPATA31B1P

Across TCGA patient cohorts, SPATA31B1P mutation is significantly associated with the RNA expression of many other genes, with 81 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SPATA31B1P-associated genes across cancer lineages are CYTH1P1, RN7SL354P, and MIR2278. Each is linked with SPATA31B1P in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA31B1P-to-partner and partner-to-SPATA31B1P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYTH1P1 grouped by SPATA31B1P-low versus SPATA31B1P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31B1P→partner) and Y-score (partner→SPATA31B1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CYTH1P1 →	+0.209	+4.184	<.001	.004	3	2
UCEC	RN7SL354P →	+0.521	+4.374	<.001	.002	3	2
SKCM	MIR2278 →	+0.183	+2.869	<.001	.004	3	1
SKCM	RNA5SP470 →	+0.342	+3.897	<.001	.009	3	1
SKCM	RPL21P9 →	+0.083	+2.746	.001	.001	3	1
SKCM	LINC00554 →	+0.006	+2.623	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 81 associations by consensus.

CYTH1P1 by SPATA31B1P expression — UCEC

Explore this box plot interactively →