SPATA31B1P

Across TCGA pan-cancer cohorts, SPATA31B1P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated SPATA31B1P data layer compared with 5 for mutation status.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher SPATA31B1P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SPATA31B1P expression acts as an unfavorable survival marker, although some lineages such as COAD and LIHC show a favorable association.

DLBC, KIRC, and UCEC are the cancer types where SPATA31B1P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Tertile	All	0.338	0.795	.010	76	view →
KIRC	DFS	Tertile	III,IV	0.589	0.790	.008	48	view →
UCEC	DFS	Tertile	All	0.502	0.674	.011	24	view →
COAD	DFS	Tertile	All	1.000	0.505	.020	21	view →
LIHC	DFS	Tertile	II,III,IV	0.895	0.411	.016	18	view →
SKCM	DFS	Tertile	IV	0.134	0.589	.031	18	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	15	view →
ACC	DFS	Tertile	All	0.254	0.554	.026	13	view →
STAD	OS	Tertile	IV	0.682	0.258	.040	9	view →
TGCT	DFS	Median	All	0.896	0.712	.005	6	view →
UCS	OS	Tertile	II,III,IV	0.834	0.521	.042	4	view →
LUSC	OS	Tertile	III,IV	0.664	0.290	.045	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

SPATA31B1P–DLBC (DFS)

Open the DLBC breakdown →