Across TCGA pan-cancer cohorts, SPATA31B1P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SPATA31B1P’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SPATA31B1P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SPATA31B1P is over-expressed in tumor.
HNSC and KIRP are the cancer types where SPATA31B1P tumor–normal differential expression is most reproducible.