SPATA2L

Across TCGA patient cohorts, SPATA2L mutation is significantly associated with the RNA expression of many other genes, with 1,331 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA2L-associated genes across cancer lineages are RNA5SP173, MIR610, and OR1L6. Each is linked with SPATA2L in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA2L-to-partner and partner-to-SPATA2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP173 grouped by SPATA2L-low versus SPATA2L-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA2L→partner) and Y-score (partner→SPATA2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP173 →	+0.258	+7.640	<.001	.009	3	2
UCEC	MIR610 →	+0.180	+2.787	.005	.003	3	2
CESC	OR1L6 →	+0.047	+4.812	<.001	.006	3	1
CESC	LINC00314 →	+0.058	+4.669	<.001	.007	3	1
CESC	OR51A9P →	+0.077	+5.060	<.001	.001	3	1
CESC	OR6B2 →	+0.060	+4.409	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,331 associations by consensus.

RNA5SP173 by SPATA2L expression — BLCA

Explore this box plot interactively →