SOX2-OT

Across TCGA patient cohorts, SOX2-OT RNA expression is significantly associated with the protein abundance of many other proteins, with 13,671 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SOX2-OT-associated proteins across cancer lineages are ZMYM3, UBXN7, and MIEF1_S59. Each is linked with SOX2-OT in more than 3 cancer types. Because this analysis shows association rather than direction, both SOX2-OT-to-partner and partner-to-SOX2-OT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOX2-OT versus ZMYM3 in HNSC, with a Pearson correlation of 0.24.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX2-OT→partner) and Y-score (partner→SOX2-OT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZMYM3 →	+0.284	+0.603	<.001	.009	3	4
LSCC	UBXN7 →	+0.635	+0.861	<.001	<.001	3	4
PDAC	MIEF1_S59 →	-0.426	-0.057	.004	<.001	3	4
GBM	PHC3_S842 →	+0.630	+0.779	.001	.001	3	4
LSCC	RER1 →	-0.371	-1.115	<.001	<.001	3	4
LSCC	ADNP →	+0.356	+1.005	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,671 associations by consensus.

SOX2-OT vs ZMYM3 — HNSC

Explore this scatter interactively →