SNRPB2

Across TCGA patient cohorts, SNRPB2 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRPB2-associated genes across cancer lineages are SNORA40C, RNU6-90P, and INSL4. Each is linked with SNRPB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRPB2-to-partner and partner-to-SNRPB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORA40C grouped by SNRPB2-low versus SNRPB2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPB2→partner) and Y-score (partner→SNRPB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SNORA40C →	+0.379	+5.497	<.001	.004	3	1
UCEC	RNU6-90P →	+0.603	+3.734	.001	<.001	3	1
UCEC	INSL4 →	+0.912	+3.753	.001	.004	3	1
UCEC	OR6K6 →	+0.073	+3.358	<.001	.006	3	1
UCEC	MAB21L2 →	+0.269	+3.805	.008	.003	3	1
UCEC	RNU1-34P →	+0.215	+4.226	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

SNORA40C by SNRPB2 expression — BLCA

Explore this box plot interactively →