SNORD116-8

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD116-8 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORD116-8-associated genes across cancer lineages are RNA5SP461, H2AB3, and BTG3P1. Each is linked with SNORD116-8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-8-to-partner and partner-to-SNORD116-8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-8→partner) and Y-score (partner→SNORD116-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRNA5SP461 →+0.468+7.816<.001.00832
SKCMH2AB3 →+0.109+7.816<.001.00831
SKCMBTG3P1 →+0.089+7.816<.001.00831
UCECRN7SL248P →+0.154+4.722<.001.00431
UCECCOX6CP3 →+0.276+3.677.003.00631
LUSCRNU6-352P →+0.256+7.924<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration