SNORD116-26

Across TCGA patient cohorts, SNORD116-26 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORD116-26-associated genes across cancer lineages are ATP6V1E1P2, COPS8P1, and MIR6821. Each is linked with SNORD116-26 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD116-26-to-partner and partner-to-SNORD116-26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP6V1E1P2 grouped by SNORD116-26-low versus SNORD116-26-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD116-26→partner) and Y-score (partner→SNORD116-26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP6V1E1P2 →	+0.567	+4.661	<.001	.004	3	1
UCEC	COPS8P1 →	+0.311	+4.748	<.001	.003	3	1
UCEC	MIR6821 →	+1.014	+4.552	<.001	.005	3	1
UCEC	RNA5SP412 →	+1.832	+4.552	<.001	.005	3	1
UCEC	RNA5SP405 →	+0.783	+5.582	<.001	.002	3	1
UCEC	RNU6-618P →	+0.658	+4.969	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

ATP6V1E1P2 by SNORD116-26 expression — UCEC

Explore this box plot interactively →