Q-omics provides the consensus-scored COPS8P1 profile across patient tissues and cancer cell-line models. COPS8P1 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, COPS8P1 is differentially expressed in 1, with the highest sampling consensus in LUSC. Additionally, COPS8P1 RNA expression shows 6,754 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, LUSC, and THYM as cancer lineages where COPS8P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for COPS8P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes COPS8P1 survival associations across molecular data types. COPS8P1 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible COPS8P1 RNA expression–survival associations across cancer types. High COPS8P1 expression shows unfavorable associations in KIRC, KICH, LIHC, SARC and READ, but favorable associations in BLCA. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for COPS8P1 RNA expression.
This table summarizes COPS8P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for COPS8P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. COPS8P1 shows higher tumor expression in LUSC. The LUSC box plot shows higher COPS8P1 RNA expression in tumor versus normal tissue (log2 FC = +0.014, t-test p = .048).
This table shows molecular features associated with COPS8P1 in patient tissues and cancer cell lines. In patient samples, COPS8P1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
