COPS8P1

Across TCGA patient cohorts, COPS8P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,051 significant associations in total. STAD shows the largest number of these associations.

The most reproducible COPS8P1-associated GO terms across cancer lineages are Establishment of protein localization to membrane, Aerobic respiration, and Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with COPS8P1 in more than 9 cancer types. Because this analysis shows association rather than direction, both COPS8P1-to-partner and partner-to-COPS8P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to membrane grouped by COPS8P1-low versus COPS8P1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS8P1→partner) and Y-score (partner→COPS8P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Establishment of protein localization to membrane →	+0.059	+0.042	<.001	.002	3	10
STAD	Aerobic respiration →	+0.067	+0.059	<.001	<.001	3	9
STAD	Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.053	+0.053	<.001	<.001	3	8
STAD	Protein insertion into membrane →	+0.056	+0.063	<.001	<.001	3	8
STAD	Protein methylation →	+0.047	+0.054	<.001	<.001	3	8
STAD	Maturation of LSU-rRNA →	+0.060	+0.060	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,051 associations by consensus.

Establishment of protein localization to membrane by COPS8P1 expression — ESCA

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