SNORD115-40

Q-omics provides the consensus-scored SNORD115-40 profile across patient tissues and cancer cell-line models. SNORD115-40 expression is associated with patient survival in 4 of 34 cancer types, with the highest sampling consensus in GBM. Additionally, SNORD115-40 RNA expression shows 8,410 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight GBM as cancer lineages where SNORD115-40 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes SNORD115-40 survival associations across molecular data types. SNORD115-40 RNA expression shows survival associations in the most cancer types (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

SNORD115-40 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	4	GBM (18)	view →

This table ranks reproducible SNORD115-40 RNA expression–survival associations across cancer types. High SNORD115-40 expression shows unfavorable associations in GBM, STAD, LIHC and LGG. The GBM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify GBM as the clearest survival context for SNORD115-40 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Tertile	All	0.135	0.418	.003	18	view →
STAD	DFS	Tertile	II,III,IV	0.147	0.525	.007	18	view →
LIHC	OS	Tertile	All	0.177	0.783	.003	18	view →
LGG	OS	Tertile	All	0.160	0.524	.004	15	view →

Pink = unfavorable, green = favorable. all 4 lineages →

SNORD115-40-GBM (OS)

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