SNORD115-40

Across TCGA pan-cancer cohorts, SNORD115-40 RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated SNORD115-40 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SNORD115-40 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNORD115-40 expression acts as an unfavorable survival marker.

STAD, GBM, and LIHC are the cancer types where SNORD115-40 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	II,III,IV	0.147	0.525	.007	18	view →
GBM	OS	Tertile	All	0.135	0.418	.003	18	view →
LIHC	OS	Tertile	All	0.177	0.783	.003	18	view →
LGG	OS	Tertile	All	0.160	0.524	.004	15	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SNORD115-40–STAD (DFS)

Open the STAD breakdown →