SNORD115-40

Across TCGA patient cohorts, SNORD115-40 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,410 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNORD115-40-associated proteins across cancer lineages are PRDM16_S549, RRBP1, and STRN3_S229. Each is linked with SNORD115-40 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-40-to-partner and partner-to-SNORD115-40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNORD115-40 versus PRDM16_S549 in PDAC, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-40→partner) and Y-score (partner→SNORD115-40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PRDM16_S549 →	-1.025	-0.244	<.001	.004	3	2
GBM	RRBP1 →	-0.376	-0.913	<.001	<.001	3	2
LUAD	STRN3_S229 →	+0.368	+0.319	.004	.004	3	2
LUAD	AVL9 →	+0.314	+0.320	.006	.001	3	2
GBM	BSCL2 →	+0.716	+1.091	<.001	.001	3	2
LUAD	CRACDL_S356 →	+0.469	+0.235	.006	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,410 associations by consensus.

SNORD115-40 vs PRDM16_S549 — PDAC

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