SNORD115-27

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD115-27 mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SNORD115-27-associated genes across cancer lineages are RN7SL543P, TAS2R39, and CDRT15P5. Each is linked with SNORD115-27 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD115-27-to-partner and partner-to-SNORD115-27 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD115-27→partner) and Y-score (partner→SNORD115-27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRN7SL543P →+0.150+4.628.001.00432
SKCMTAS2R39 →+0.081+4.500<.001.00531
SKCMCDRT15P5 →+0.061+5.199<.001.00331
SKCMAK3P4 →+0.211+4.440<.001.00631
UCECCDRT15P8 →+0.248+5.081<.001.00831
LUADOR7E8P →+0.076+5.343<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

Exploration