Across TCGA pan-cancer cohorts, SNORD115-27 RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated SNORD115-27 data layer compared with 1 for mutation status.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SNORD115-27 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD115-27 expression acts as an unfavorable survival marker.

STAD, GBM, and LIHC are the cancer types where SNORD115-27 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	All	0.102	0.736	<.001	54	view →
GBM	OS	Tertile	All	0.089	0.413	.015	18	view →
LIHC	OS	Tertile	All	0.140	0.783	.002	18	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SNORD115-27 tumor-vs-normal RNA expression · all SNORD115-27 data types