AK3P4

Q-omics provides the consensus-scored AK3P4 profile across patient tissues and cancer cell-line models. AK3P4 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in ESCA. Additionally, AK3P4 RNA expression shows 5,809 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight ESCA, and STAD as cancer lineages where AK3P4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes AK3P4 survival associations across molecular data types. AK3P4 RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

AK3P4 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	12	ESCA (98)	view →

This table ranks reproducible AK3P4 RNA expression–survival associations across cancer types. High AK3P4 expression shows unfavorable associations in ESCA, UVM, LGG, COAD, KICH and MESO. The ESCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify ESCA as the clearest survival context for AK3P4 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Quartile	All	0.538	0.736	.002	98	view →
UVM	OS	Tertile	II,III,IV	0.218	0.718	.006	72	view →
LGG	OS	Tertile	All	0.156	0.456	<.001	54	view →
COAD	DFS	Tertile	All	0.626	0.806	<.001	45	view →
KICH	OS	Tertile	All	0.788	0.970	.006	42	view →
MESO	DFS	Tertile	II,III,IV	0.039	0.407	<.001	36	view →

Pink = unfavorable, green = favorable. all 12 lineages →

AK3P4-ESCA (OS)

Explore this curve interactively →