AK3P4

Across TCGA pan-cancer cohorts, AK3P4 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated AK3P4 data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher AK3P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated AK3P4 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

ESCA, UVM, and LGG are the cancer types where AK3P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Quartile	All	0.538	0.736	.002	98	view →
UVM	OS	Tertile	II,III,IV	0.218	0.718	.006	72	view →
LGG	OS	Tertile	All	0.156	0.456	<.001	54	view →
COAD	DFS	Tertile	All	0.626	0.806	<.001	45	view →
KICH	OS	Tertile	All	0.788	0.970	.006	42	view →
MESO	DFS	Tertile	II,III,IV	0.039	0.407	<.001	36	view →
OV	OS	Tertile	IV	0.281	0.795	<.001	36	view →
SKCM	OS	Tertile	II,III,IV	0.970	0.816	.018	27	view →
READ	DFS	Tertile	All	0.143	0.620	.003	27	view →
THCA	DFS	Tertile	All	0.095	0.868	<.001	27	view →
PCPG	DFS	Tertile	All	0.813	0.923	.026	18	view →
GBM	DFS	Tertile	All	0.093	0.245	.028	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

AK3P4–ESCA (OS)

Open the ESCA breakdown →