SMYD3-IT1

Across TCGA patient cohorts, SMYD3-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,015 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SMYD3-IT1-associated proteins across cancer lineages are RPRD2_S928, HNRNPU, and SRRT. Each is linked with SMYD3-IT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SMYD3-IT1-to-partner and partner-to-SMYD3-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SMYD3-IT1 versus RPRD2_S928 in GBM, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SMYD3-IT1→partner) and Y-score (partner→SMYD3-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPRD2_S928 →	+0.562	+0.738	<.001	<.001	3	5
GBM	HNRNPU →	+0.331	+0.765	<.001	<.001	3	5
GBM	SRRT →	+0.369	+0.645	<.001	.002	3	5
HNSC	PARP1 →	+0.385	+0.720	<.001	<.001	3	5
PDAC	SMYD3 →	+0.366	+0.453	.006	.003	3	5
GBM	RCOR3 →	+0.492	+0.752	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,015 associations by consensus.

SMYD3-IT1 vs RPRD2_S928 — GBM

Explore this scatter interactively →