Across TCGA patient cohorts, SMPD4P1 mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SMPD4P1-associated genes across cancer lineages are RNU4ATAC7P, MIR1197, and RN7SL601P. Each is linked with SMPD4P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SMPD4P1-to-partner and partner-to-SMPD4P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SMPD4P1→partner) and Y-score (partner→SMPD4P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU4ATAC7P →	+0.278	+8.055	<.001	.007	3	1
BRCA	MIR1197 →	+0.306	+7.731	<.001	.009	3	1
BRCA	RN7SL601P →	+0.133	+7.731	<.001	.009	3	1
SKCM	ZFRP1 →	+0.009	+4.624	<.001	.005	3	1
SKCM	FABP7P2 →	+0.191	+3.893	.003	.004	3	1
SKCM	MRPS18BP2 →	+0.053	+3.533	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

SMPD4P1 survival (RNA) · tumor vs normal (RNA) · all SMPD4P1 data types